203 – Curcumin C3 Complex for Inflammation – My interview with Dr. Anurag Pande, PhD

47 Clinical Studies Confirm the Benefits of Curcumin C3 Complex


Inflammation & Pain Support

CLICK on image for more interviews on inflammation and pain.

Curcumin (turmeric extract) has become one of the fastest growing and likely most beneficial herbs we have. With good reason: Curcumin exerts its benefits across a wide range of health conditions. Because its role in calming inflammation is so dramatic and the science is so compelling curcumin has become one of the worlds most important herbal extracts. Its popularity is unrivaled among herbs at this  point in time.

Because of this popularity, there are many sources of curcumin on the market. Many of these sources are providing curcumin extracts that have virtually no clinical evidence for their safety or effectiveness. How do we as consumers have confidence in a product? How do we know if a particular form of curcumin is effective and safe? We now know that there are synthetic analogs of curcumin that are very difficult to detect using traditional methods. The cheaters are very sophisticated. So how do we identify effective products?

When we take supplements, we all want to get the benefits that we have heard about. We know what the benefits are because some of the extracts have been clinically studied. The studies reveal the safety. The studies reveal the benefits. The studies reveal the effective dosage. The studies verify no toxicity. This is how we know and have confidence in particular products. My goal is to help you identify good companies with good science.

C3_ComplexWhen we want to understand the benefits of curcumin we can look to Sabinsa C3 Complex. This particular curcumin extract has 47 clinical studies going back to 1998. This is more than any other curcumin product. In this interview, I am speaking to Dr. Anurag Pande, PhD about these scientific studies using C3 Complex.

“The Role of Inflammation
Most degenerative diseases are driven by chronic, sub-clinical inflammation. The old view of inflammation is that it represents the healing process. This is true to a certain extent; however when inflammation becomes chronic, it becomes a disease.

Today the study of inflammation has gone from the tissue levels deeper into the nuclear level. Cell-signaling molecules have been identified which stimulate the genes that induce the expression of the COX enzyme, which in turn induces inflammation.

InflammationBeneficial Effects of Curcuminoids

  • Curcumin C3 Complex is an effective “Bioprotectant”, antioxidant quenching free radicals and also preventing their formation.
  • Curcumin has been shown to be a COX 2 (Cyclooxygenase-2) inhibitor.
  • Unlike conventional non steroidal anti-inflammatory drugs (NSAIDs), curcuminoids do not cause gastrointestinal side effects or ulcers.
  • Curcuminoids support a healthy immune system
  • Prevent connective tissue break down through inhibiting destructive enzymes

Nutraceutical Applications of Circurcuminoids

  • Curcumin_BenefitsAntioxidant support
  • Alzheimer’s disease/dementia
  • Cardiovascular support
  • Immune support/ Anti-tumor/Anticancer effects  Anti-inflammatory support
  • Wound healing for example: Rheumatoid arthritis, postoperative inflammation, colorectal cancer, bladder cancer, oral leucoplakia, psoriasis, antiviral effects.” Excerpt from Curcuminoids.com.

About Dr. Anurag Pande, PhD
Curry Powder to Clinical SignificanceDr. Pande is the Vice-President of Scientific Affairs for Sabinsa. Dr. Pande holds a Ph.D. in Phytochemistry. He has both a Masters Degree in Science and a Bachelor’s Degree in Science. He is the author of several trade and peer reviewed publications. He is a contributor to the book “Curry Powder to Clinical Significance”.

Dr. Pande has been with Sabinsa’s sister company, Sami Labs, since 2004 in a research capacity, and spent several years at Sabinsa Japan’s Tokyo office as Senior Technical Manager. Today, Dr. Pande works from Sabinsa’s Corporate HQ based in East Windsor, NJ, USA.

About Sabinsa
Sabinsa Corporation, founded in 1988, is a manufacturer and supplier of herbal extracts, cosmeceuticals, minerals and specialty fine chemicals. Sabinsa’s mission is to provide alternative and complementary natural products for human nutrition and well-being. Over the past twenty years, Sabinsa has brought to market more than 100 standardized botanical extracts and privately funded several clinical studies in conjunction with prestigious institutions in support of these products. Its present operations have grown to employ 1000 people worldwide in ten manufacturing, R&D and distribution facilities. Additionally, botanical cultivation efforts undertaken by the organization now total nearly 40,000 acres to ensure sustainable supplies on its key products. All products intended for human consumption are certified Kosher and Halal.


{ 3 comments… read them below or add one }

1 Nagesh Dwivedi May 18, 2016 at 3:41 am

Compair to yellow turmeric White Turmeric is Better in Melanin inhibition from root cause by blocking of Alpha MSH and MC-1R Receptor also blocks Tyrosinase and Eumelanin .


2 Steve Lankford May 18, 2016 at 8:58 am

I have not seen or heard of the studies on white turmeric. Our conversation is on yellow turmeric extract from Sabinsa not turmeric root or powder so the comparison isn’t really relevant for this discussion. I would love to review any science on white turmeric if you care to forward it to me. Thanks.


3 Steve Lankford May 18, 2016 at 5:08 pm

Here is a response by Dr. Pande
“The white curcuminoids or Tetrahydrocurcuminoids are metabolites of the curcumin which body forms when curcumin is ingested. Infact the published studies on the Sabinsa’s Tetrahydrocurcuminoids show that these metabolites may hold key to understand the curcumin metabolism and activity in human body. Now on the effect on the eumelanin or tyrosinase, these effects (tyrosinase inhibition/ melanogenesis inhibitory activity of THC have been studied for the topical application. Topical application of C3 Reduct (Sabinsa’s brand of Tetrahydrocurcuminoids) has been linked to skin lightening activity in cosmeceutical products and is already commercialized. Sabiwhite which is pure form of Tetrahydrocurcumin is clinically studied for its safety and efficacy for its topical application and compared against hydroquinone. Infact Sabinsa holds a patent on Tetrahydrocurcuminoids as well.”


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