309 – The Endocannabinoid System – Part 1 – Endo Calm

Naturally address your body’s response to stress and anxiety
My Interview with Dr. Jeffrey Burke

Brain Support

This will be the first interview in a series of 5 that will focus on the endocannabinoid system (ECS) and the nutrients that have been scientifically and clinically evaluated for their specific benefits to the ECS. The discovery of the ECS and the recent explosion in interest in CBD (cannabidiol) is unprecedented. However what is often overlooked is that there are many other nutrients and herbs that can also affect the ECS.

In this 5 interviews series with Dr. Jeffrey Burke we will cover in great detail the ECS, what it is, what it does and certain nutrients and products beyond CBD that can be used for 5 common health concerns. We all love CBD and its benefits to human health, however some people don’t benefit from CBD, some people can’t use CBD and other nutritional products may work better that CBD. The more you know the better choices you will make. The best products are the ones that work best for you and that is your process of discovery.

The Healing Power of the Endocannabinoid System

In addition to the interviews with Dr. Burke, I will be excerpting portions from the book The Healing Power of the Endocannabinoid System by Dr. Michael Murray, ND. Dr. Murray’s booklet is available free from Emerald Health Bioceuticals and at better health food stores. This book is a wonderful introduction to the ECS including CBD and the other plants and nutrients for you to consider. Here’s three other ways to get the book:

Click this link to view and/or download a FREE PDF of the book. OR

  • Contact Emerald Health at
  • Request free book offer with code word “health quest”
  • OR
  • Email to: info@emeraldhealthbio.com 

If you would like a very good overview of this topic you should listen to my interview with Jade Beutler, CEO of Emerald Health Bioceuticals. Here is link to that previous interview.

In this first of the series we will be discussing Endo Calm. Endo Calm is a natural calming solution that addresses your body’s response to stress and anxiety by supporting the following:

  • Healthful response to daily stress, fear and anxiety.*
  • Feelings of relaxation and greater mental energy.*
  • Adrenal function and normal cortisol levels.*
  • Positive changes in the balance of body and mind.*
  • Supports the Endocannabinoid Receptor Sites.*
  • Supports the production of Endocannabinoids.*
  • Supports the retention of Endocannabinoids.*

We will examine the following products once a month for 5 months, this interview being the first one. Additionally we will discuss in greater detail the unique benefits of each product:

  • Endo Bliss – supports a positive outlook and resistance to daily pressure.*
  • Endo Sleep – supports a restful and rejuvenating sleep.*
  • Endo Brain – supports mental acuity and cognition.*
  • Endo Inflame – supports your body’s healthy response to pain and inflammation.*

Following is excerpt from The Healing Power of the Endocannabinoid System co-authored by Dr. Michael Murray

ECS 101 – What we know and how we learned it

IN 1964, ISRAELI RESEARCHER Dr. Raphael Mechoulam identified THC as the main active ingredient in cannabis. Three decades later, he began studying exactly how THC works in the body and brain. That led to his discovery of a complex and elegant cell-signaling system triggered by not only THC, but other compounds as well.

Dr. Mechoulam named this system endocannabinoid because “endo” means within the body and “cannabinoid” highlights the role the cannabis plant played in the discovery.

To put the magnitude of this discovery into perspective, an ECS exists in all mammals, birds, reptiles, and other invertebrates. And despite the relative infancy of the monumental discovery of the ECS, there have been over 20,000 studies published in the last 20 years containing the word “cannabinoid.”

The biological nuts and bolts of the ECS   The ECS is presently known to include:

  • Receptor sites on cells called CB1 and CB2
  • Compounds known as endocannabinoids produced in the body from dietary fats like anandamide that bind to CB1 and CB2 receptors
  • Enzymes that impact the manufacture and metabolism of these endocannabinoids

Receptors send vital information to cells, organs, and the nervous system, and are critical to maintaining optimal health and homeostasis. In the human body, the ECS is believed to have more cellular receptor sites than any other receptor system.

Basically, receptors on cell surfaces are similar to locks on a door. When the right “key,” in the form of a chemical molecule, binds to the cellular receptor, it relays a specifc message to the cell that helps it do its job. Most hormones work in this manner. For example, when insulin binds to its receptor on a cell, it causes that cell to ultimately allow blood sugar (glucose) to enter the cell.

The two primary cell cannabinoid receptors, CB1 and CB2, are found throughout the body. However, they tend to concentrate in certain areas. For example, CB1 receptors are abundant in the brain, while CB2 receptors are more often found on immune cells, in the gastrointestinal tract, and in the peripheral nervous system.

The widespread distribution of cannabinoid receptors shows just how important the ECS is to overall bodily function and health. In fact, activation of CB1 and CB2 receptors changes cellular function, including gene expression and electrical excitability of cell membranes. It is a very powerful event.” End excerpt.

We will cover more aspects of the ECS and the unique products from Emerald Health Bioceuticals is this upcoming series. If you would like to receive notice when each interview is posted, you can sign up for email notices on the home page. The email will contain a link so you can go right to the interview. You can unsubscribe at any time and we will never spam you or share your address.

CLICK HERE for links to all available interviews on Emerald Health Bioceuticals.

About Dr. Jeffrey Burke – Dr. Burke has been in the health and nutrition field for well over three decades. Dr. Burke went back to school to become a Naturopathic Physician and a Master Herbalist, and received his degree in 2012. In August of 2012, he was inducted into the Nevada Broadcasting Hall Of Fame. Dr. Burke’s passion is spreading the word on nutrition. Dr. Burke does a daily radio show in Las Vegas called The Staying Healthy Show.

{ 2 comments… read them below or add one }

1 http://www.cbdoilkansascity.com February 1, 2019 at 4:08 am

If there’s only a more believable proof that we have such a system in our body..


2 Steve Lankford February 1, 2019 at 8:40 am

Search PubMed for “endocannabinoid system”

There are over 5000 reported studies. How much is enough?


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